Bono has injured his arm while riding a bicycle in New York City.
A post on U2’s website says Bono “injured his arm in a cycling spill in Central Park” and will require surgery to repair it.
The posting by The Edge, Adam Clayton and Larry Mullen did not say when or how the accident happened.
The band also said they will have to reschedule their planned week-long appearance on the US TV programme Tonight Show with Jimmy Fallon.
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NBC confirmed that U2, who had been booked to appear every day this week, had pulled out due to the accident.
Just last week, German authorities said Bono’s private plane lost a hatch as it was coming in for a landing at Berlin’s airport.