Saturday (3.0 unless stated)
Manchester United (4) v Newcastle (15), 12.45 - Live BT Sport 1
Sergio Romero will continue in goal for Manchester United, as Real Madrid target David de Gea sits out another game. Centre back Phil Jones is absent with mild thrombosis and fellow defender Marcos Rojo is lacking match sharpness. Bastian Schweinsteiger could make his first start in midfield, but Marouane Fellaini is suspended.
New signing Florian Thauvin goes straight into the Newcastle squad. He could be joined by fellow midfielder Moussa Sissoko, who is recovering well from a groin problem. Midfielder Siem de Jong is back in training after a shin injury, as is defender Paul Dummett following a hamstring problem, but full back Daryl Janmaat is suspended.
Last season: Newcastle 0 Man Utd 1, Man Utd 3 Newcastle 1
Top scorers (all competitions): Memphis Depay (Man Utd) 2; Papiss Cisse & Georginio Wijnaldum (Newcastle) 1
Match odds: H 1-3 A 8-1 D 19-5
Referee: Craig Pawson
Crystal Palace (7) v Aston Villa (10)
Midfielder Jack Grealish could be in the Aston Villa squad for the first time this season after recovering from a hamstring injury. Carles Gil (ankle) and new signing Adama Traore may also be involved at Selhurst Park. Jores Okore remains out with a knee injury while Jose Angel Crespo is still working his way back from a groin problem.
Crystal Palace have no new injury worries. Goalkeeper Julian Speroni (finger) and striker Marouane Chamakh (hamstring) are back in training but will not be risked. Winger Bakary Sako could join the squad for the first time since his switch from Wolves.
Last season: Aston Villa 0 Crystal Palace 0, Crystal Palace 0 Aston Villa 1
Top scorers (all competitions): Damien Delaney, Yohan Cabaye, Wilfried Zaha & Joel Ward (Crystal Palace) 1; Rudy Gestede (Aston Villa) 1
Match odds: H 5-6 A 18-5 D 23-10
Referee: Keith Stroud
Leicester (2) v Tottenham (14) - Live Setanta Sports 1
Midfielder Gokhan Inler could make his Leicester debut after joining from Napoli. Matty James continues to recover from a long-term knee injury while Christian Fuchs is expected to recover from illness to feature in the squad.
Tottenham manager Mauricio Pochettino could field new forward recruit Clinton N’Jie at some stage. Midfielder Andros Townsend is not available due to an ankle injury, but striker Harry Kane has recovered from a tight calf which saw him substituted during last weekend’s draw against Stoke.
Last season: Tottenham 4 Leicester 3, Leicester 1 Tottenham 2
Top scorers (all competitions): Riyad Mahrez (Leicester) 3; Eric Dier, Nacer Chadli (Tottenham) 1
Match odds: H 13-8 A 8-5 D 12-5
Referee: Martin Atkinson
Norwich (9) v Stoke (13)
Norwich boss Alex Neil has no new injury concerns and could retain the team that won 3-1 at Sunderland last weekend. Defender Martin Olsson (shoulder) and forward Kyle Lafferty (knee) miss out but both should return to contention for their next league outing at Southampton.
Winger Xherdan Shaqiri is set for his Stoke debut and playmaker Bojan Krkic could make his first-team comeback after a long-term knee injury. Defender Marc Wilson is another who could make his first senior appearance of the season having shaken off an ankle complaint. Striker Peter Odemwingie (hamstring) and centre back Ryan Shawcross (back) are sidelined.
Last season: No corresponding fixture
Top scorers (all competitions): Nathan Redmond (Norwich) 2; Marko Arnautovic & Mame Biram Diouf (Stoke) 1
Match odds: H 7-5 A 2-1 D 11-5
Referee: Mike Dean
Sunderland (20) v Swansea (6)
Sunderland will be without centre back Younes Kaboul who is struggling with a knee injury, which could mean a first appearance of the season for skipper John O'Shea. Spanish midfielder Jordi Gomez remains sidelined with the knee injury that has delayed his start to the season.
Midfielder Ki Sung-yueng remains a doubt for Swansea after suffering a hamstring injury on the opening day of the season at Chelsea. He is Swansea’s only injury concern as manager Garry Monk seeks to build on a positive start which has seen the Welsh club take four points from their opening two games.
Last season: Swansea 1 Sunderland 1, Sunderland 0 Swansea 0
Top scorers (all competitions): Steven Fletcher, Duncan Watmore & Jermain Defoe (Sunderland) 1, Bafetimbi Gomis & Andre Ayew (Swansea) 2, Match odds: H 13-5 A 11-10 D 9-4
Referee: Neil Swarbrick
West Ham (8) v Bournemouth (19)
West Ham goalkeeper Adrian begins a three-match suspension following his red card against Leicester, and Republic of Ireland netminder Darren Randolph is expected to be his replacement. Mauro Zarate (hamstring) has joined fellow strikers Enner Valencia (leg) and Andy Carroll (knee) in the treatment room, while midfielder Reece Oxford is a doubt due to a niggle.
Bournemouth manager Eddie Howe is expected to name an unchanged side. Shaun MacDonald is available after the midfielder recovered from a toe injury but absent are Harry Arter, who has a groin injury, and Christian Atsu, who has a back problem.
Last season: No corresponding fixture
Top scorers (all competitions): Mauro Zarate (West Ham) 2.
Match odds: H 11-8 A 19-10 D 12-5
Referee: Jon Moss
Sunday
West Brom (18) v Chelsea (16), 1.30 - Live Sky Sports 1
Striker and Tottenham target Saido Berahino is set to face Chelsea despite persistent speculation over his West Brom future. Defender Federico Fazio has been lined up as an arrival from Tottenham while, among the forwards, Serge Gnabry is fit and hoping for a debut and £12 million record buy Salomon Rondon is expected to make his home bow.
Pedro and Baba Rahman could make their Chelsea debuts after joining this week. Goalkeeper Thibaut Courtois will return from a one-match ban in place of Asmir Begovic, while captain John Terry is likely to start in defence despite being substituted at half-time in last week’s loss at Manchester City. Victor Moses and Oscar are out with undisclosed injuries.
Last season: West Brom 3 Chelsea 0, Chelsea 2 West Brom 0
Top scorers: Oscar (Chelsea) 1
Match odds: H 9-2 A 4-6 D 13-5
Referee: Mark Clattenburg
Everton (5) v Manchester City (1), 4.0 - Live Sky Sports 1
Everton boss Roberto Martinez intends to pick John Stones despite Chelsea's interest in the defender. Midfielders Muhamed Besic and Kevin Mirallas could play after being unused substitutes in last Saturday's 3-0 win at Southampton following hamstring and ankle problems respectively, and winger Aiden McGeady has recovered from his hamstring complaint. Steven Pienaar (hamstring), Darron Gibson (foot), Tony Hibbert (knee) and Leighton Baines (ankle) remain sidelined.
Manchester City are without right back Pablo Zabaleta whose knee injury could sideline him for a month. New signing Nicolas Otamendi is a likely substitute, with captain Vincent Kompany and Eliaquim Mangala doing well in central defence recently. Midfielders Fabian Delph and Fernando are back in contention after injury.
Last season: Everton 1 Man City 1, Man City 1 Everton 0
Top scorers (all competitions): Ross Barkley & Romelu Lukaku (Everton) 2; Yaya Toure & Vincent Kompany (Man City) 2
Match odds: H 7-2 A 8-11 D 14-5
Referee: Anthony Taylor
Watford (12) v Southampton (17), 4.0
New signing Alessandro Diamanti could make his Watford debut. Defender Miguel Britos and goalkeeper Giedrius Arlauskis are available for their first appearances after serving bans given at their previous clubs. Defender Nathan Ake is expected to be on the bench after arriving on loan from Chelsea. Beyond long-term absentee Joel Ekstrand, manager Quique Flores has a fully fit squad.
Southampton could start with Jay Rodriguez as he looks for his first Premier League goal in 17 months, with Manchester United target Sadio Mane also likely to be included. Ryan Bertrand (knee) and Jordie Clasie (hamstring) remain unavailable, as does long-term absentee Fraser Forster (knee).
Last season: No corresponding fixture
Top scorers (all competitions): Miguel Layun & Odion Ighalo (Watford) 1; Graziano Pelle (Southampton) 3
Match odds: H 7-4 A 13-8 D 11-5
Referee: Andre Marriner
Monday
Arsenal (11) v Liverpool (3), 8.0 - Live Sky Sports 1
Arsenal have no fresh injury worries. Midfielder Jack Wilshere is not expected back until after the international break as he continues his recovery from a hairline fracture to his left fibula. Striker Danny Welbeck (knee) is also sidelined while midfielder Tomas Rosicky remains a longer-term absentee after knee surgery.
Liverpool will assess the fitness of captain Jordan Henderson, who was withdrawn early in the second half of last Monday’s defeat of Bournemouth. Henderson had been taking pain-killers for a foot injury. The return of midfielder Joe Allen (hamstring) remains uncertain while striker Daniel Sturridge continues to recover from hip surgery and defender Jon Flanagan (knee) is out until December.
Last season: Arsenal 4 Liverpool 1, Liverpool 2 Arsenal 2
Top scorers (all competitions): Olivier Giroud & Alex Oxlade-Chamberlain (Arsenal) 1; Philippe Coutinho & Christian Benteke (Liverpool) 1
Match odds: H 8-11 A 18-5 D 14-5
Referee: Michael Oliver
