Argentina captain Agustin Pichot returns to the Pumas side for Saturday's World Cup clash with Namibia.
Pichot had been struggling with a hamstring injury but will lead Argentina in the Pool D match at Stade Velodrome in Marseille.
Stade Francais outhalf Juan Martin Hernandez is sidelined with a thigh injury so Felipe Contepomi takes the number 10 jersey, switching from inside centre.
Only three forwards remain from the 33-3 victory over Georgia with Patricio Albacete, Juan Martin Fernandez Lobbe and Juan Manuel Leguizamon retaining their places.
Federico Todeschini, whose World Cup was in doubt because of a calf injury, has been included on the bench.
In total there are nine changes to the team that defeated Georgia.
Argentina: I Corleto; H Senillosa, G Tiesi, M Contepomi, H Agulla; F Contepomi, A Pichot (captain); R Roncero, AV Basualdo, O Hasan, C Fernandez Lobbe, P Albacete, L Ostiglia, JM F Lobbe, J Leguizamon. Replacements: M Ledesma, JM Scelzo, R Kairelis, G Longo, N Fernandez Miranda, F Todeschini, F Miras.
