3.4m people in England may have had Covid-19, study shows

Testing programme for antibodies by Imperial College London involved 100,000 volunteers

Some 3.4 million people in England have been infected with Covid-19, a figure far higher than previous estimates, a study suggests.

The results come from the world's largest home testing programme to find antibodies for the coronavirus, a study involving more than 100,000 volunteers and carried out by Imperial College London.

Conducted with the use of a simple finger-prick home test said to be easy and accurate enough for mass surveillance studies, the programme suggested 6 per cent of England’s population had already been infected with Covid-19 by July 13th.

The 3.4 million people that represents is many times higher than the tally of known cases for the entire UK as posted by Johns Hopkins University in the US – whose aggregated numbers have become the main reference for monitoring the disease – and which listed the country's case numbers at 315,546 as of Thursday morning.

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The study tracked the spread of infection across England after the pandemic’s first peak, with volunteers testing themselves at home between June 20th and July 13th.

People living in London were most likely to have been infected, along with those working in care homes and health care, people from black, Asian and other minority ethnic groups, and people living in larger households.

The programme suggested a total of 13 per cent of people living in London had Covid-19 antibodies, compared with less than 3 per cent in the southwest of England.

People working in care homes (16 per cent) and health care (12 per cent) returned far higher results than people who were not key workers, at 5 per cent.

The study found 17 per cent of black volunteers had antibodies, the categories of Asian and “other” ethnic minorities had 12 per cent each. The figure among white volunteers was only 5 per cent.

People aged from 18-34 showed the highest incidence of antibodies, at 8 per cent, while over-65s had the lowest rate at just 3 per cent.

Volunteers in the most deprived areas of the country were slightly more likely to have antibodies than those in the wealthiest areas, at 7 per cent compared with 5 per cent, while those in households of more than six or seven people (12 per cent and 13 per cent) were more likely to have had Covid-19 than those in single or two-person households (5 per cent).

Smokers were slightly less likely to have antibodies than non-smokers – at 3 per cent compared with 5per cent – while 32 per cent of people with antibodies had shown no symptoms, a figure which rose to 49 per cent of those aged older than 65.

Health minister Edward Argar hailed the study as an important development in Britain's fight against coronavirus.

“Large-scale antibody surveillance studies are crucial to helping us understand how the virus has spread across the country and whether there are specific groups who are more vulnerable, as we continue our work to drive down the spread of the disease,” Mr Argar said in a statement.

“We don’t yet know that antibodies provide immunity to coronavirus, but the more information we can gather on this virus, and the easier we can make it for people to participate in these studies, the better equipped we will be to respond.

“The British public have already played a massive part in helping to keep the country safe and I’d urge them to consider signing up to one of the many vital surveillance studies taking place over the coming months as part of our national testing effort.”

The study’s authors also cautioned there was still no firm evidence the presence of antibodies meant people could not be re-infected with the virus.

Professor Graham Cooke, the research professor of infectious diseases and research lead at Imperial, said: "Using the finger-prick tests suitable for large scale home testing has given us clearest insight yet into the spread of the virus in the country and who has been at greatest risk.

“These data will have important implications as decisions to ease lockdown restrictions in England.” – PA