The US Food and Drug Administration approved the first-ever nasal spray emergency treatment for opioid overdose on Wednesday.
The spray, developed by privately held Adapt Pharma, the latest venture of serial pharmaceuticals entrepreneur Seamus Mulligan, uses naloxone, a drug used to treat opioid overdose for nearly 45 years but approved only in injectable forms.
Data from the Centers for Disease Control and Prevention indicates opioid overdose led to about 23,500 deaths in the United States in 2013, a four-fold jump from 1999.
A majority of these deaths occur in non-medical settings, stressing the need for user-friendly treatments that can be administered without the help of a medical practitioner, Mr Mulligan said.
The treatment, Narcan, which Adapt plans to launch by January, is expected to have wide coverage under health insurance with affordable co-pays, Mr Mulligan added.
Adapt bought the development and commercialisation rights to Narcan from London-based Lightlake Therapeutics in December 2014.
Group purchasers will be able to purchase the spray at a discounted price of $37.50 per 4 mg device, Mr Mulligan said.
