Arsenal (2) v Chelsea (9)

Top scorer Thierry Henry may have to settle for a place on the bench even though he has recovered from an ankle injury. Tony Adams (flu) joins Gilles Grimandi, Oleg Luzhny, Kanu and Lauren on the Highbury sick-list. England goalkeeper David Seaman (shoulder/ankle) should come back after three months out, as should centre-back Martin Keown (hamstring).

Marcel Desailly (dead leg) is a worry, but Sam dalla Bona and Mario Melchiot are ready to return. Dennis Wise is likely to keep his favoured spot in central midfield. Albert Ferrer is fit again, but Winston Bogarde (knee) is out.

Last season: Arsenal 2 Chelsea 1, Chelsea 2 Arsenal 3.

Last five league matches: Arsenal D L W D L; Chelsea W L W D W.

Top scorers: Thierry Henry (Arsenal) 14, Jimmy Floyd Hasselbaink (Chelsea) 15.

Match odds: H 8-11 A 10-3 D 11-5.

Referee: D Elleray.

Aston Villa (11) v Liverpool (5)

Aston Villa are without suspended midfielders Lee Hendrie and George Boateng. Turkish international Alpay returns after suspension and injury, while midfielder Ian Taylor (hamstring) and wing back Mark Delaney (knee) are trying to shake off their knocks.

Robbie Fowler could return to action after missing out on the midweek League Cup defeat at Crystal Palace because he was unable to train following a late-night fracas the previous week. Jari Litmanen could make his full debut after coming on as a substitute at Palace.

Last season: Liverpool 0 Aston Villa 0, Aston Villa 0 Liverpool 0.

Last five league matches: Aston Villa D D W L L; Liverpool L W W L W.

Top Scorers: Dion Dublin (Aston Villa) 5, Emile Heskey (Liverpool) 15.

Match Odds: H 8-5, A 7-5, D 21-10.

Referee: G Barber.

Bradford (20) v Manchester Utd (1)

Benito Carbone is not even guaranteed a place on the bench after being put up for sale along with Stan Collymore. Dan Petrescu has already left Valley Parade after joining Southampton.

Nicky Butt is doubtful after suffering cuts and bruises picked up during the FA Cup win at Fulham. Fabien Barthez returns in goal after being out with flu. Striker Teddy Sheringham is in contention for a start while Andy Cole and Jaap Stam could figure.

Last season: Bradford 0 Man Utd 4, Man Utd 4 Bradford 0.

Last five league matches: Bradford D L L L W; Man Utd L W W D W.

Top Scorers: Benito Carbone and Dean Windass (Bradford) 5. Teddy Sheringham (Man Utd) 16

Match Odds: H 6-1, A 2-5, D 11-4.

Referee: A Wiley.

Everton (16) v Tottenham (12)

Kevin Campbell should be back in the squad after recovering from a virus, but the chances of pairing him with Duncan Ferguson for the first time look slim. Ferguson has a hand injury following the break-in at his home last weekend and a hamstring problem following last Saturday's FA Cup win at Watford.

Spurs skipper Sol Campbell and striker Les Ferdinand face fitness tests on hamstring injuries. Full-back Steve Carr, Norway striker Steffen Iversen, German midfielder Steffen Freund and Argentinian defender Mauricio Taricco are out.

Last season: Everton 2 Tottenham 2, Tottenham 3 Everton 2.

Last five league matches: Everton L D L L L; Tottenham D D L L W.

Top Scorers: Francis Jeffers (Everton) 7. Les Ferdinand and Sergei Rebrov (Tottenham) 7.

Match Odds: H 6-5, A 9-5, D 11-5.

Referee: A D'Urso

Manchester City (19) v Leeds Utd (14)

Midfielder Jeff Whitley has recovered from his knee injury, but Gerard Wiekens is out, as are long-term casualties Kevin Horlock and Mark Kennedy. Paulo Wanchope is back from international duty, but Darren Huckerby (ankle) is extremely doubtful.

Mark Viduka (flu) and Robbie Keane (knee) are both struggling to be fit, but midfielder Lee Bowyer is again available after serving a one-match ban. Rightback Gary Kelly (knee) is out along with Harry Kewell (calf).

Last season: No Corresponding fixture.

Last five league matches: Man City D L D L D; Leeds L W L L D

Top Scorers: Paulo Wanchope (Man City) 12, Mark Viduka (Leeds) 14.

Match Odds: H 6-4, A 11-8, D 23-10.

Referee: M Dean.

Middlesbrough (18) v Derby (15)

Keith O'Neill could return at wing back for Middlesbrough after suspension. But striker Noel Whelan faces a late fitness test on a back injury.

Derby will be without influential defender Taribo West, who is on international duty for Nigeria. Craig Burley, Rory Delap and Darryl Powell all return to the squad after injury.

Last season: Middlesbrough 1 Derby 4, Derby 1 Middlesbrough 3.

Last five league matches: Middlesbrough W D W D D; Derby W W D L W.

Top Scorers: Alen Boksic (Middlesbrough) 8, Malcolm Christie (Derby) 10.

Match Odds: H 4-5, A 11-4, D 23-10.

Referee: R Styles.

Newcastle (8) v Coventry (17)

Newcastle loan signing Wayne Quinn will be handed a Premiership debut. The Sheffield United wing-back will definitely start the game, and midfielder Gary Speed is expected to be fit again.

Coventry's Moroccan players Youssef Chippo and Mustapha Hadji are on international duty and will miss tomorrow's match. John Aloisi is expected to play as a striker with John Eustace going into midfield.

Last season: Newcastle 2 Coventry 0, Coventry 4 Newcastle 1.

Last five league matches: Newcastle W L W D L; Coventry L D W D D.

Top Scorers: Alan Shearer (Newcastle) 7, John Aloisi and Craig Bellamy (Coventry) 6.

Match Odds: H 8-13, A 4-1, D 9-4.

Referee: J Winter.

Southampton (13) v Charlton (7)

Southampton manager Glenn Hoddle welcomes back defender Dean Richards who has been suffering from flu for the last two weeks. Moroccan Tahar El Khalej is unavailable on international duty, but midfielder Hassan Kachloul has been cleared to play. New signing Dan Petrescu could also feature.

Alan Curbishley will use his ninth different striking combination in 23 Premiership matches with Matt Svensson partnering South African Shaun Bartlett up front. Midfielder Graham Stuart returns from suspension, but captain Mark Kinsella is still missing with a knee problem.

Last season: No Corresponding fixture.

Last five league matches: Southampton L D W W L; Charlton L W L W W.

Top Scorers: James Beattie (Southampton) 10, Jonatan Johansson (Charlton) 13.

Match Odds: H 10-11, A 12-5, D 9-4.

Referee: P Taylor.

West Ham (10) v Sunderland (3)

West Ham duo Michael Carrick (hamstring) and Trevor Sinclair (knee) look set to miss out but Paolo Di Canio is back after missing the last two matches with a heavy cold.

Sunderland striker Niall Quinn and defender Michael Gray will both return. Quinn has shaken off a back problem, while Gray is fit again after ankle and hamstring injuries.

Last season: Sunderland 1 West Ham 0, West Ham 1 Sunderland 1.

Last five league matches: West Ham D D L W L; Sunderland L W W D W.

Top Scorers: Frederic Kanoute (West Ham) 10, Kevin Phillips (Sunderland) 12.

Match Odds: H 11-10, A 2-1, D 11-5.

Referee: M Messias.

Sunday

Ipswich (4) v Leicester (6)

Ipswich hope central defender Mark Venus will recover from a bruised thigh. Alun Armstrong, ineligible for the League Cup tie against Birmingham last Tuesday, is set to return alongside 15goal Marcus Stewart up front.

Goalkeeper Tim Flowers and Gerry Taggart are ruled out with thigh problems. Darren Eadie (knee) and Frank Sinclair (calf) are also injured.

Last season: No Corresponding fixture.

Last five league matches: Ipswich W L D W L; Leicester L W W L L.

Top Scorers: Marcus Stewart (Ipswich) 15, Muzzy Izzet (Leicester) 7.

Match Odds: H 10-11, A 12-5, D 9-4.

Referee: M Riley.