Saturday

(Current league positions in brackets)

Barnsley (16) v Tottenham (10)

Barnsley have doubts over midfielder Sean McClare, who is suffering from a foot injury, and defender Adie Moses, who cut his head and had eight stitches inserted during the 1-0 defeat by Crystal Palace last Sunday. Darren Sheridan (broken jaw) and Matt Appleby (torn groin ligaments) are sidelined.

Darren Anderton is back for Tottenham after being rested from the midweek Premiership win over Southampton. Allan Nielsen is likely to make way, while defenders Ramon Vega and Justin Edinburgh may also earn recalls. George Graham must choose between Chris Armstrong, Steffen Iversen and Les Ferdinand for two positions up front after the latter missed the last two games recovering from a head injury.

Last season: No corresponding fixture.

Last five league matches: Barnsley D D D L L, Tottenham D D D D W.

Top scorers: Craig Hignett (Barnsley) 10; Chris Armstrong (Tottenham) 12.

Match odds: H 7-2; A 4-5; D 2-1.

Referee: M Reed (Birmingham).

Arsenal (3) v Derby (9)

Arsenal have Patrick Vieira serving a onematch ban and Emmanuel Petit and Remi Garde sidelined by ankle injuries. Stephen Hughes looks a certain starter, and Nelson Vivas, Fredrik Ljungberg and Nwankwo Kanu come into contention.

Derby have fitness worries over Tony Dorigo and Horacio Carbonari. Dorigo is nursing a damaged hamstring, and Carbonari has a groin problem. Lars Bohinen could also miss out because his wife is expecting a baby this weekend. Captain Igor Stimac is back after suspension, and midfielder Darryl Powell has recovered from a neck injury.

Last season: No corresponding fixture.

Last five league matches: Arsenal W W D W D, Derby W L W L D.

Top scorers: Nicolas Anelka (Arsenal) 15; Paulo Wanchope (Derby) 6.

Match odds: H 1-2; A 11-2; D 12-5.

Referee: S Dunn (Bristol).

Sunday

Newcastle (12) v Everton (15)

With Gary Speed suspended, Croatian midfielder Silvio Maric and club captain Rob Lee will battle it out for a place in the starting 11, although the England midfielder is favourite to partner Dietmar Hamann after coming on as a substitute in his side's last two games.

Everton have midfielder Tony Grant available after a hamstring problem, while Don Hutchison is back following a one-match suspension. But Frenchman Olivier Dacourt and teenage stars Michael Ball and Richard Dunne are banned.

Last season: No corresponding fixture.

Last five league matches: Newcastle W W W L D, Everton L L W L D.

Top scorers: Alan Shearer (Newcastle) 13; Ibrahima Bakayoko (Everton) 5.

Match odds: H 4-6; A 4-1; D 11-5.

Referee: G Barber (Pryford, Surrey)

Manchester Utd (1) v Chelsea (2)

Manchester United teenager Wes Brown comes in for the suspended Jaap Stam, and Ronny Johnsen is ruled out with a groin strain. Brown looks certain to play in the centre of defence alongside Henning Berg, with Gary Neville remaining at right-back.

Chelsea have Gianluca Vialli, Dennis Wise, Frank Leboeuf and Celestine Babayaro suspended, and Michael Duberry and Gustavo Poyet are still out injured. Tore Andre Flo will partner Gianfranco Zola up front, while Bernard Lambourde is expected to retain his place in central defence, and Jody Morris and Bjarne Goldbaek should step into starting roles in midfield.

Last season: No corresponding fixture.

Last five league matches: Man Utd W W D W W, Chelsea L W D W W.

Top scorers: Dwight Yorke (Man Utd) 24; Gianfranco Zola, Gustavo Poyet (Chelsea) 11.

Match odds: H 10-11; A 5-2; D 9-4.

Referee: P Durkin (Portland, Dorset).

Odds supplied courtesy of William Hill.