Saturday
Bolton v Charlton
Bolton have defender Mark Fish and midfielder Ricardo Gardner back from international duty. Fish has returned after South Africa were knocked out of the African Nations Cup, while Gardner is back following Jamaica's first-round exit from the CONCACAF Gold Cup. Paul Warhurst is out with a long-term hamstring injury, while Gareth Farrelly is suspended.
Charlton have skipper Mark Kinsella back in contention after missing three matches with a stomach virus. Kinsella came through 80 minutes of a reserve game on Wednesday. Manager Alan Curbishley will be forced to make one change to the team which beat Fulham on Tuesday night as recent signing Mathias Svensson is cup-tied.
Top scorers: Gudjohnsen (Bolton) 14; Hunt (Charlton) 18
Match odds: H 7-4 A 5-4 D 11-5
Referee: U Rennie (Sheffield)
Sunday
Chelsea v Gillingham
Jon Harley is set to continue as left back for Chelsea in the expected absence of AWOL Nigerian Celestine Babayaro. Chelsea are already short of defenders with Frank Leboeuf suspended, Emerson Thome cup-tied and Graeme Le Saux, Jes Hogh and Albert Ferrer recovering from ankle injuries - although the latter may be on the bench. John Terry is set to partner Marcel Desailly in the centre of defence while Gianfranco Zola could partner George Weah up front. Jody Morris is favourite to replace Dennis Wise, who starts a two-match ban, but Finnish striker Mickael Forssell is back in the squad.
Gillingham striker Carl Asaba is pushing hard to be involved at Chelsea after recovering from a long-term hernia problem. He is expected to start on the bench but manager Peter Taylor is considering starting him alongside Andy Thomson. Taylor is expecting Adrian Pennock to recover from a hamstring problem, while Mark Saunders looks likely to overcome a slight calf strain.
Top scorers: Flo (Chelsea) 13; Thomson (Gillingham) 12
Match odds: H 1-6 A 11-1 D 9-2
Referee: P Durkin (Portland)
Everton v Aston Villa
David Unsworth returns from suspension for Everton and Richard Gough is expected to recover from a hip injury. Unsworth will return to left back, Danny Cadamarteri will also drop to the bench with Michael Ball playing wide on the left of midfield, unless John Collins is found a midfield slot.
Finnish Under-21 international goalkeeper Peter Enckelman is on alert to make his FA Cup debut for Villa if David James is sidelined by a thigh strain. Midfielders Ian Taylor and Lee Hendrie are fit after ankle problems, but look like having to settle for places on the bench, alongside wing-back Steve Watson, who has served a one-match ban. Striker Gustavo Bartelt is bidding to make his debut after joining from Roma on loan.
Top scorers: Campbell (Everton) 12; Dublin (Aston Villa) 12
Match odds: H 5-4 A 7-4 D 11-5
Referee: D Gallagher (Banbury, Oxon)
Tranmere v Newcastle
Irish Under-21 midfielder Alan Mahon is Tranmere's main worry after damaging his ankle in the midweek defeat at Wolves, but Rovers are confident he will be fit. David Kelly, Graham Allen, Gary Jones and Gareth Roberts are all now clear of suspensions. Manager John Aldridge is without Clint Hill while Steve Yates is not fully match fit. Top scorer Wayne Allison, rested at Wolves in midweek, will also return.
Defender Steve Howey returns to the Newcastle squad for the first time since rupturing his Achilles tendon in last season's FA Cup semi-final. Midfielder Rob Lee is suspended, and although Nikos Dabizas (thigh), Duncan Ferguson (back), Didier Domi (ankle) and Temuri Ketsbaia (tonsilitis) have all missed training this week, they are all included in the party for the trip to Birkenhead.
Top scorers: Allison (Tranmere) 14; Shearer (Newcastle) 27
Match odds: H 11-4 A 5-6 D 11-5
Referee: S Dunn (Bristol)