. THE circumstances under which the anti-D vaccine, manufactured by the Blood Transfusion Service Board, was infected;
. when thee BTSB first became aware that the virus was hepatitis C;
. the BTSB's response to that discovery;
. the BTSB's response to a letter in 1991 from Middlesex Hospital which showed a link between hepatitis C and the anti-D vaccine;
. whether the National Drugs Advisory Service carried out its functions properly;
. whether supervision of the BTSB and NDAB was adequate in the light of the functional and statutory responsibilities of the Minister for Health, his Department and the Health Boards;
. the questions raised by Mrs Brigid McCole's family in an open letter after her death;
. whether anti-D was a therapeutic substance and whether the granting of a manufacturer's licence between 1970-1984 would have been appropriate and could have prevented the infection of human immunoglobulin anti-D with hepatitis C.