Real Madrid midfielder Claude Makelele will miss this week's Champions League semi-final second leg against Juventus in Turin.
Makelele, a French international, strained a thigh muscle in Saturday's draw at Recreativo Huelva and will be sidelined for two weeks.
Ronaldo's chances of playing against the Serie A champions are also very slim, according to medical staff.
The Brazilian striker injured his calf during last week's 2-1 first leg win at the Bernabeu.
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But Zinedine Zidane and Luis Figo appear to have shaken off minor injury worries and should play.
Striker Raul will also be available after making a quicker-than-expected recovery from an appendix operation.