Irish Farmers’ Association (IFA) president Pádraig Walshe said despite enduring very difficult conditions, farmers separated issues with Government policy from the importance of membership of the European community.
"Farm families have a huge stake in the future of Europe," said Mr Walshe.
"They recognise the importance of staying at the heart of Europe, and working with our European colleagues to get the best results for the agri-food sector in this country."
"Farm families were not distracted by bogus claims or false arguments. They know that our Yes vote will best position the IFA to defend Irish agriculture and meet future challenges in Europe."
The Irish Business and Employers Confederation (Ibec) said the decision was good for Ireland and Europe.
"The vote is an important step on the road to economic recovery and the restoration of Ireland's international reputation," director general Danny McCoy said. "Work must now continue on repairing the Irish banking system and bringing order to the public finances."